LITTLE KNOWN FACTS ABOUT PHENOBARBITAL SODIUM WATER SOLUBILITY.

pentobarbital decreases effects of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of CYP3A4 inducers may decrease sufentanil concentrations and efficacy, quite possibly precipitating withdrawal syndrome in patients who may have made physical dependence to sufentanil. Discont